Jennifer Aniston (Series Premiere)
Megan Mullally
Sean Hayes/Nikki Reed
Amanda Bynes/Sharon Stone/Thicke
Jennifer Love Hewitt/John C. McGinley
Peter Boyle/Eve
Terry Bradshaw/Kim Cattrall/Seal
Noah Wyle/Bob Guiney/Elton John
Sean Astin/Breckin Meyer
Richard Simmons/Randy Jackson
Neve Campbell/Ruben Studdard
Merv Griffin/Topher Grace
Jessica Capshaw/The Thrills
Kim Cattrall/Bobby J. Thompson
Betty White/Amy Smart/Gavin DeGraw
Burt Reynolds/Nick Gannon
Ashton Kutcher/Deidre Hall/Travis
Julie Bowen/Fefe Dobson
Amy Brenneman and LeAnn Rimes
Katey Segal/Chris Harrison/Brian McKnight
Seth Green/Tyra Banks
Charlize Theron/Brook Shields
Diane Lane/Missy Elliot
Naomi Watts/Shoshana Johnson/Five For Fighting
Meg Ryan/Jason Lewis/The Indigo Girls
Jessica Simpson / Nick Lachey / Henry Winkler
Sarah Michelle Gellar/Olivier Martinez/Brad Paisley
Ben Affleck/Sara Rue
Katie Holmes, Black Eyed Peas
Season 1 Halloween Show: Ellen as Dr. Phil
Kiefer Sutherland, Jane Leeves
Jeff Bridges, Doris Roberts
Steve Harvey, Rod Stewart
Holly Hunter, Sarah McLachlan, Jeff Corwin
Lauren Graham, Frankie Muniz
Brendan Fraser, John Stamos
Queen Latifah, Sheryl Crow
Eric McCormack, Paul Walker
Jenna Elfman, Cyndi Lauper
Bernie Mac, Valerie Bertinelli
Robert Downey Jr., Mary J. Blige
Bette Midler, Bob Guiney
Dwayne The Rock Johnson, Jami Gertz
David Duchovny, Poppy Montgomery
Anne Hathaway, Cedric the Entertainer
Jessica Simpson & Nick Lachey, Henry Winkler, Hugh Dancy
Elisha Cuthbert, Dennis Franz
Barry Manilow, Nia Vardolas, Baby Birds
Janet Jackson, David Arquette, Ellen's Own Award Show
John Travolta, Goran Visnjic, Random Acts of Kindness
Tina Fey, David Bowie, Ellen's 'In Case of Emergency'
Isabella Rossellini, Debbie Reynolds, Bill Rancic
Simon Baker, Cheri Oteri
Christopher Walken, Tim Meadows
Jennifer Garner, Jamie Kennedy
Dakota Fanning, Rebecca Romijn, Feline Reunion
Bill Cosby, Sarah Chalke
Mary Tyler Moore, Rosie Perez, Hidden Talents
Jay Leno, Lorraine Bracco
Lindsay Lohan, Kevin Sorbo, Ending of ‘Friends’
Hugh Jackman, Al Roker, Car Giveaway
Josh Duhamel, Christina Ricci
David Schwimmer from ‘Friends,’ Gabrielle Union
Patti LaBelle, Cynthia Nixon
Usher, Patrick Stewart, Cooking with Nigella Lawson
Paula Abdul, Wilmer Valderrama
David Spade, Latoya London, Vanessa Marcil
Simon Cowell, Jorja Fox
Dolly Parton, Jon Favreau, Workout Attire
Glenn Close, Andy Richter
Jake Gyllenhaal, Sean Hayes, 8-Year-Old Drummer
Antonio Banderas, Alanis Morissette
Cameron Diaz, Cotton Candy
Halle Berry, Tom Selleck
Kate Hudson, Julian McMahon
Justin Timberlake, Sharon Stone, Fantasia Barrino